Neurotransmitter Table
Neuro transmitter | Receptor Subtype | Location/Function/Effects/symptoms of excess or deficit if applicable | Distribution (ie: CNS/PNS, GI, vascular) | Drug classes that target this neurotransmitter or receptor | Specific medications that target this neurotransmitter or receptor |
Glutamate | AMPA | ||||
NMDA | |||||
GABA | GABA a | ||||
GABA b | |||||
Serotonin 5HT | 5HT 1a | ||||
5HT 1B | |||||
5HT 1d | |||||
5HT 1E | |||||
5HT 1F | |||||
5HT 2A | |||||
5HT2B | |||||
5HT 2C | |||||
5HT 3 | Ligand gated ion channels. highest levels in the brain stem- Targets: decreases nausea/emesis Will inhibit the release of NE and Ach- Targets: cognition, anxiety, addiction. | CNS (chemoreceptor trigger zone) PNS: GI tract (vagal nerve) | Antiemetics Antidepressants | Antiemetics: ondansetron, granisetron, dolasetron, palonosetron Antidepressants: Mirtazapine vortioxetine | |
5HT 4 | |||||
5HT 5 AB | |||||
5HT6 | |||||
5HT 7 | |||||
NE norepinephrine | α 1 | ||||
α 2 | |||||
DA Dopamine | D1 | ||||
D2 | |||||
D3 | |||||
D4 | |||||
Ach Acetylcholine | Muscarinic | ||||
Nicotinic | |||||
Histamine | |||||
Melatonin |
1. For each neurotransmitter and receptor type, complete the following columns:
a. Location/function/effects/symptoms of excess or deficit
b. Distribution
c. Drug classes that target this neurotransmitter or receptor
d. All neurotransmitters and receptor types: Specific medications that target this neurotransmitter or receptor
2. This criterion is linked to a Learning Outcome Organization
3. Font is consistent throughout table, and grammar, spelling, and/or punctuation are accurate.
A total of 4 references needed with intext citation. 2 references provided below. Please use 7th edition APA scholarly references that are witin 5 years.
Stahl, S.M. (2020). Stahl’s essential psychopharmacology: Prescribers guide (7th ed.). Cambridge University Press.
Stahl, S. M. (2021). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (5th ed.). Cambridge University Press.